Stermitz F R, Suess T R, Fink N H, Puzziferri N
J Nat Prod. 1981 Nov-Dec;44(6):693-5. doi: 10.1021/np50018a013.
Fifty-four species of plants from 36 genera and 21 families were collected in the mountains and high plains of northern Colorado. Extracts were tested for alkaloids, cytotoxicity, antitumor activity and IP toxicity in mice. A few were tested for insect attractant or deterrent properties. Alkaloids were found in 23 species, 15 showed cytotoxicity, and 27 exhibited IP toxicity. Four extracts showed insect deterrent properties, and three proved to attractant. None of the extracts showed useful antitumor activity. High alkaloid content and/or activity in several of the screens can be used to identify species and genera worthy of detailed phytochemical investigation.
在科罗拉多州北部的山区和高平原收集了来自21科36属的54种植物。对提取物进行了生物碱、细胞毒性、抗肿瘤活性和对小鼠的腹腔注射毒性测试。少数提取物还测试了昆虫引诱或驱避特性。在23种植物中发现了生物碱，15种表现出细胞毒性，27种表现出腹腔注射毒性。四种提取物表现出昆虫驱避特性，三种被证明有引诱作用。没有一种提取物显示出有效的抗肿瘤活性。几个筛选中高生物碱含量和/或活性可用于识别值得进行详细植物化学研究的物种和属。
