Pecker J, Scarabin J M, Dekkiche M, Allaire C
Neurochirurgie. 1981;27(5):287-93.
The natural history of malignant gliomas is compared to the mean survival duration after surgery alone and/or surgery associated with radiotherapy and chemotherapy. In the state of the art a combined treatment by surgery and roentgentherapy offers the best prognosis but does not allow for more than 35% of expectation of life at the end of the first year. According to the severity of the general prognosis the present authors advocate a strict care for the functional integrity. An improved knowledge in the biology of cerebral gliomas justifies further consideration in the surgical treatment preparing the expected effects of radiotherapy and chemotherapy.
将恶性神经胶质瘤的自然病史与单纯手术后和（或）手术联合放疗及化疗后的平均生存时间进行了比较。在目前的技术水平下，手术联合放射治疗可提供最佳预后，但在第一年末的预期寿命不超过35%。根据总体预后的严重程度，本文作者主张严格关注功能完整性。对脑胶质瘤生物学的进一步了解为手术治疗中考虑放疗和化疗的预期效果提供了依据。
