Herman Z S, Plech A, Bień E, Wieloch-Depta L, Jez W
Pol J Pharmacol Pharm. 1981;33(5):485-9.
The effect of some cholinolytics, cholinomimetics and atypical antidepressants on behavior of rats forced to swim (in the "behavioral despair test") was investigated. In addition, the relation between the test performance and the inborn level of exploratory and locomotor activities was studied. Cholinomimetics prolonged, while cholinolytics and antidepressants shortened the immobility phase ("despair reaction"). The "despair reaction" was less pronounced in rats with high motor exploratory activity level.
研究了某些胆碱能阻滞剂、拟胆碱药和非典型抗抑郁药对被迫游泳大鼠行为（“行为绝望试验”）的影响。此外，还研究了试验表现与探索和运动活动的先天水平之间的关系。拟胆碱药延长了不动期（“绝望反应”），而胆碱能阻滞剂和抗抑郁药则缩短了不动期。在运动探索活动水平高的大鼠中，“绝望反应”不太明显。
