Friman G, Ilbäck N G, Pilström L
Scand J Clin Lab Invest. 1981 Oct;41(6):551-6. doi: 10.3109/00365518109090497.
The activities of LD isozymes were studied by thermoinactivation in skeletal muscle biopsies from young and old patients suffering from viral, mycoplasma or bacterial infections and from corresponding controls. The activities of LD2-5 decreased 35-45% and that of LD1 17-29% in the muscle of the patients compared to that of the controls. There were no differences between age groups. In the controls good correlations were demonstrated between the relative activities of the LD isozymes and the muscle fibre composition, but such correlations could not be found in the patients. This indicates that the decrease of the activity of muscle LD in these infections is not associated with alterations in any specific muscle fibre type but rather with an effect of a general reduction of the LD activity.
通过热失活法研究了年轻和老年病毒、支原体或细菌感染患者及相应对照组骨骼肌活检标本中乳酸脱氢酶（LD）同工酶的活性。与对照组相比，患者肌肉中LD2 - 5的活性降低了35 - 45%，LD1的活性降低了17 - 29%。各年龄组之间无差异。在对照组中，LD同工酶的相对活性与肌纤维组成之间存在良好的相关性，但在患者中未发现此类相关性。这表明在这些感染中肌肉LD活性的降低与任何特定肌纤维类型的改变无关，而是与LD活性普遍降低的影响有关。
