Abrahamsen A F, Høst H
Scand J Haematol. 1981 Apr;26(4):306-10. doi: 10.1111/j.1600-0609.1981.tb01666.x.
Between 1970 and 1975, 73 patients with surgically staged IA and IIA Hodgkin's disease, localized above the diaphragm, were treated with mantle field irradiation only. 24 patients relapsed during the first 5 years after the primary treatment, but 14 of them obtained long-lasting complete remission after retreatment. 23 patients with lymphocyte-depleted histology, more than 3 sites involved or a mediastinal mass of more than 6 cm had a high relapse rate (60%); these patients need treatment additional to the mantle field irradiation. The other 50 patients had an 80% relapse-free survival, 96% complete remission after treatment of the first relapse, and 98% survival after 8 years. We propose that such patients should receive mantle field irradiation only, as the primary treatment.
1970年至1975年间，73例手术分期为IA和IIA期、病变局限于横膈以上的霍奇金病患者仅接受斗篷野照射治疗。24例患者在初次治疗后的前5年内复发，但其中14例在再次治疗后获得了持久的完全缓解。23例组织学为淋巴细胞消减型、病变累及3个以上部位或纵隔肿块超过6 cm的患者复发率较高（60%）；这些患者除斗篷野照射外还需要其他治疗。其他50例患者的无复发生存率为80%，首次复发治疗后完全缓解率为96%，8年后生存率为98%。我们建议，这类患者应仅接受斗篷野照射作为初始治疗。
