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[冠状动脉静脉动脉化作为急性心肌缺血的一种治疗措施。I. 小型猪的实验研究与形态学]

[Arterialization of the coronary veins as a therapeutic measure in acute myocardial ischemia. I. Experimental studies and morphology in miniswine].

作者信息

Sedlarik K, Ebner E, Weidenbach H, Riedel E, Danz J

出版信息

Z Exp Chir. 1981;14(5):273-86.

PMID:7336804
Abstract

Mortality and morbidity of the acute myocardial infarction show an increasing tendency. The therapy, on the other hand, is not much satisfying yet. A myocardial ischemia was produced in 48 minipigs by ligature of the ramus interventricularis anterior of the left coronary artery. Its satellite vein was arterialised by means of plastic shunt. The majority of the animals of the control group without arterialisation did not survive. Electron microscopical controls showed only minimal damages of the ultrastructures in animals after arterialisation of the coronary veins.

摘要

急性心肌梗死的死亡率和发病率呈上升趋势。另一方面,其治疗效果仍不尽人意。通过结扎左冠状动脉前室间支,在48只小型猪身上制造了心肌缺血。其卫星静脉通过塑料分流术实现动脉化。未进行动脉化的对照组大多数动物未能存活。电子显微镜检查显示,冠状动脉静脉动脉化后的动物超微结构仅有轻微损伤。

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