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[家族性地中海热、补体、冷纤维蛋白原、秋水仙碱(作者译)]

[Familial Mediterranean fever, complement, cryofibrinogen, colchicine (author's transl)].

作者信息

Wautier J L, Mosesson M, Dervichian M, Cattan D

出版信息

Ann Med Interne (Paris). 1981;132(7):472-4.

PMID:7337322
Abstract

The components C1, C4, C2, C3 of the complement system were measured in a group of 24 patients with Familial mediterranean fever (F.M.F.). The presence of cryofibrinogen and its analysis was performed in the same patient. C4, C2, C3, were increased in the F.M.F. group. Cryofibrinogenemia was found in 42 p. 100 of the patients. The cryofibrinogen was composed of fibrin, fibrinogen and plasma fibronectin. The cryofibrinogen was less frequent in the group of patients treated by colchicine (p less than 0.02).

摘要

在一组24例家族性地中海热(F.M.F.)患者中检测了补体系统的C1、C4、C2、C3成分。对同一组患者检测了冷纤维蛋白原的存在情况并进行了分析。F.M.F.组中C4、C2、C3升高。42%的患者发现有冷纤维蛋白原血症。冷纤维蛋白原由纤维蛋白、纤维蛋白原和血浆纤连蛋白组成。在接受秋水仙碱治疗的患者组中,冷纤维蛋白原血症的发生率较低(p<0.02)。

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