一项关于家兔实验性鼻窦炎的研究。

A study of experimental sinusitis in rabbits.

作者信息

Maeyama T

出版信息

Auris Nasus Larynx. 1981;8(2):87-97. doi: 10.1016/s0385-8146(81)80005-3.

Abstract

Sinusitis was experimentally induced in rabbits by injecting one ml of casitone semi-liquid agar containing Staphylococcus aureus 209P in the order of 10(7) per ml into rabbit's bilateral paranasal sinuses (which had been sensitized with a 2.5% concentration of a purified egg white albumin solution) through a percutaneous route with a sterilized syringe. Two weeks after the last injection the rabbits were sacrificed and dissected. Light microscopic (LM) and scanning electron microscopic (SEM) examination of pathomorphological changes in this experimental model revealed that chronic inflammation developed in the mucous membranes of the paranasal sinuses at a high incidence.

摘要

通过经皮途径，用无菌注射器将1毫升每毫升含10⁷个金黄色葡萄球菌209P的酪蛋白胨半液体琼脂注入兔双侧鼻窦（已用2.5%浓度的纯化蛋清白蛋白溶液致敏），在兔身上实验性诱发鼻窦炎。最后一次注射两周后，处死并解剖兔子。对该实验模型病理形态学变化的光镜（LM）和扫描电镜（SEM）检查显示，鼻窦黏膜慢性炎症的发生率很高。