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缺血性心脏病与尸检时脂肪组织中氢化脂肪和反刍动物脂肪的比例:一项病例对照研究。

Ischaemic heart disease and the proportions of hydrogenated fat and ruminant-animal fat in adipose tissue at post-mortem examination: a case-control study.

作者信息

Thomas L H, Scott R G

出版信息

J Epidemiol Community Health. 1981 Dec;35(4):251-5. doi: 10.1136/jech.35.4.251.

DOI:10.1136/jech.35.4.251
PMID:7338699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1052172/
Abstract

Fatty acids characteristic of ruminant-animal fat have been found to be present in significantly lower proportions in samples from the depot fat of persons dying of ischaemic heart disease (cases) than in specimens from persons dying of unrelated causes (controls). Although such acids are also present, in lesser amounts, in hydrogenated marine oils, this case-versus-control difference is difficult to explain other than on the basis that controls consumed a higher proportion of ruminant-animal fat in their total dietary fat than did the cases. The proportions of polyunsaturated acids and of certain higher (C20 and C22 mostly mono-enoic) acids in the depot fat of cases and controls are virtually identical. There is also no indication of any difference in degrees of saturation of fats between the case and control specimens.

摘要

已发现死于缺血性心脏病患者(病例组)储存脂肪样本中反刍动物脂肪特有的脂肪酸比例,显著低于死于其他原因的人群(对照组)样本中的比例。尽管氢化海鱼油中也含有少量此类脂肪酸,但病例组与对照组之间的这种差异很难解释,除非是基于对照组在其总膳食脂肪中摄入的反刍动物脂肪比例高于病例组这一原因。病例组和对照组储存脂肪中多不饱和脂肪酸以及某些高级脂肪酸(主要是C20和C22单烯酸)的比例几乎相同。病例组和对照组样本之间的脂肪饱和度程度也没有任何差异迹象。

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J Epidemiol Community Health. 1983 Mar;37(1):16-21. doi: 10.1136/jech.37.1.16.
4
Ischaemic heart disease and consumption of hydrogenated marine oils in England and Wales.英格兰和威尔士的缺血性心脏病与氢化海产油的消费情况
J Epidemiol Community Health. 1992 Feb;46(1):78-82. doi: 10.1136/jech.46.1.78.

本文引用的文献

1
Hydrogenated oils and fats: the presence of chemically-modified fatty acids in human adipose tissue.氢化油脂:人体脂肪组织中化学改性脂肪酸的存在情况。
Am J Clin Nutr. 1981 May;34(5):877-86. doi: 10.1093/ajcn/34.5.877.
2
Trends in fat disappearance in the United States, 1909-65.1909 - 1965年美国脂肪消失的趋势。
J Nutr. 1967 Oct;93(2):Suppl:1-28. doi: 10.1093/jn/93.suppl_2.1.
3
Mortality from arteriosclerotic disease and consumption of hydrogenated oils and fats.动脉粥样硬化疾病导致的死亡率与氢化油脂的消费情况。
Br J Prev Soc Med. 1975 Jun;29(2):82-90. doi: 10.1136/jech.29.2.82.