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[接种疫苗的家禽对新城疫的血清学反应及抵抗力]

[Serological response and resistance to Newcastle disease in vaccinated poultry].

作者信息

Gerganov G, Surtmadzhiev K, Petkov M

出版信息

Vet Med Nauki. 1981;18(8):19-24.

PMID:7340102
Abstract

Studies was the titer of antihemagglutinins of a total of 3263 serum samples taken from birds routinely vaccinated against Newcastle disease, originating from various poultry farms of the country. Chosen were 139 birds in which a weak serologic response was established through spray, aerosol, and injectable live vaccines (strain La Sota, Komarov). These birds were challenged by intramuscular application of 10(6) ELD50/bird of a velogenic viscerotropic virus of ND. High specific resistance was established in the various groups of birds regardless of the low level of serum antihemagglutinins. In all such cases individual birds of the flock responded after vaccination with a high titer of serum antibodies, so the application of an active vaccine was indicated.

摘要

研究了从该国各家禽养殖场定期接种新城疫疫苗的鸟类采集的总共3263份血清样本的抗血凝素效价。选择了139只鸟,通过喷雾、气溶胶和注射活疫苗(La Sota株,科马罗夫)确定其血清学反应较弱。这些鸟通过肌肉注射每只10(6) ELD50的新城疫速发型嗜内脏型病毒进行攻毒。尽管血清抗血凝素水平较低,但在不同组的鸟类中都建立了高特异性抵抗力。在所有这些情况下,鸡群中的个别鸟类接种疫苗后血清抗体效价较高,因此表明应使用活性疫苗。

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