Angelov A, Stomonyakov V, Boev M, Silyamova V, Minev T, Vladova T
Acta Physiol Pharmacol Bulg. 1981;7(3):47-54.
The changes in the P3-wave of averaged auditory evoked potentials (AEP) from Fz, Cz and Pz were studied under conditions when: (I) the subject was required to predict which of the two alternative sound stimuli would appear. After presentation of a series of 50 high (1200 Hz) and 50 low (800 Hz) tones, in random order (mixed signal series) we proceeded suddenly to the presentation of the low tone only, without warning the subject (pseudo-mixed series); (II) the same mixed signal series was presented again requiring quick motor response by the subject only to the appearance of the high tone and not requiring verbal prediction (choice RT task). It has been found that in the three recordings: (1) the P3-wave increases for both types of stimuli, both in the situation of verbal stimulus prediction without motor response and in the situation of choice RT task; (2) the increase in P3 (assessed by the N1-P3 amplitude) is greater in AEP from stimuli disconfirming the prediction compared with stimuli confirming it; (3) preforming of the verbal prediction, in the course of the pseudo-mixed series, to prediction of the appearance of the low tone only is accompanied by a sharp decrease or disappearance of the P3-wave. The results show that the P3-wave is not connected with the development of motor potentials but with the processes of verbal prediction, in particular with the non-coincidence between the event expected by the subject and the really appearing one.
在以下条件下，研究了从Fz、Cz和Pz记录的平均听觉诱发电位（AEP）中P3波的变化：（I）要求受试者预测两种交替出现的声音刺激中哪一种会出现。在以随机顺序呈现一系列50个高音（1200赫兹）和50个低音（800赫兹）的音调（混合信号系列）后，我们突然只呈现低音，且未事先告知受试者（伪混合系列）；（II）再次呈现相同的混合信号系列，要求受试者仅对高音的出现做出快速运动反应，而不要求言语预测（选择反应时任务）。研究发现，在这三种记录中：（1）在言语刺激预测但无运动反应的情况下以及在选择反应时任务的情况下，两种类型的刺激都会使P3波增大；（2）与证实预测的刺激相比，来自与预测不符的刺激的AEP中P3波的增大（通过N1 - P3波幅评估）更大；（3）在伪混合系列过程中，仅对低音出现进行言语预测时，会伴随着P3波的急剧下降或消失。结果表明，P3波与运动电位的产生无关，而是与言语预测过程有关，特别是与受试者预期事件和实际出现事件之间的不一致有关。
