byford R L, Riner J L, Kocan K M, Stratton L G, Hair J A
Am J Vet Res. 1981 Dec;42(12):2088-9.
Sustained-release oxytetracycline boluses (20%) delivering 145 to 150 mg/bolus/day were administered to complement-fixation test-negative cattle at dosages of 2.0, 2.5, and 3.0 mg/kg of body weight. Subsequent challenge exposure of cattle with Dermacentor andersoni Stiles infected with Anaplasma marginale Theiler indicated that treatment with the dosage of 2.5 mg/kg prevented clinical anaplasmosis and that treatment with the dosage of 3.0 mg/kg prevented disease infection.
向补体结合试验呈阴性的牛投喂持续释放的土霉素大丸剂(20%),剂量为2.0、2.5和3.0毫克/千克体重,每丸每日释放145至150毫克。随后,用感染了边缘无形体泰勒亚种的安氏革蜱对牛进行攻击感染,结果表明,2.5毫克/千克的剂量治疗可预防临床无形体病,3.0毫克/千克的剂量治疗可预防疾病感染。