Fontanel J P, Meriel P, Goron S, Diallo B, Descrozailles J M
Ann Otolaryngol Chir Cervicofac. 1981;98(9):465-9.
The authors report on the experiment carried out on the use of sodium nitroprusside (NPS) in otological surgery. The acknowledged advantages of NPS over hypotensors and more particularly its spécifically vascular, périphéral, swift action, rapidly reversible, are worth mentioning. Control over the achieved hypotension however, requires careful attention to avoid overdosage which could result in severe hypotension and "cyanhydric" intoxication. The recording of capillary pulse constitutes an easy and reliable solution to the difficulties arising from permanent control of blood-pressure and of peripheral arterial perfusion. The method both produces excellent results permitting bloodless surgery, and allows a reduction of NPS doses giver, without resorting to a invasive for measuring blood pressure. The method used in surgical fields other than otology has already proved very satisfactory.
作者报告了关于硝普钠(NPS)在耳科手术中应用的实验。与其他降压药相比,NPS公认的优势,尤其是其特定的血管、外周、快速起效且迅速可逆的作用,值得一提。然而,要控制好所达到的低血压状态,需要格外小心以避免过量用药,否则可能导致严重低血压和“氰化物”中毒。记录毛细血管搏动是解决持续监测血压和外周动脉灌注所产生困难的一种简便可靠的方法。该方法既能产生出色的效果,实现无血手术,又能在不借助侵入性血压测量的情况下减少硝普钠的给药剂量。该方法在耳科以外的手术领域已经被证明非常令人满意。