Rogers M P, Hutchinson I
Biochem J. 1981 Nov 15;200(2):453-6. doi: 10.1042/bj2000453.
In an incubation system in vitro with fully activated Intralipid as substrate, rat high-density lipoprotein inhibits the hydrolysis of triacylglycerol by lipoprotein lipase from rat adipose tissue, but does not inhibit hydrolysis by the enzyme from bovine milk. The pattern of inhibition suggests that substrate and high-density lipoprotein may compete for association with rat adipose-tissue lipoprotein lipase.
在以完全活化的脂肪乳剂为底物的体外孵育系统中,大鼠高密度脂蛋白抑制大鼠脂肪组织脂蛋白脂肪酶对三酰甘油的水解,但不抑制牛乳中该酶的水解。这种抑制模式表明底物和高密度脂蛋白可能竞争与大鼠脂肪组织脂蛋白脂肪酶的结合。