Poller L
Ric Clin Lab. 1978 Oct-Dec;8(4):237-47.
Oral anticoagulant treatment is widely administered, particularly for the management and prophylaxis of thrombo-embolism. Anticoagulant dosage requires laboratory monitoring. An international system of standardization of laboratory control is necessary. A system based on the provision of a standardized tissue extract of thromboplastin (British Comparative Thromboplastin) is described. This is used in laboratories in seventy countries including a representative group of Italian hospitals and is now recommended as the international reference preparation.
口服抗凝治疗应用广泛，尤其用于血栓栓塞的管理和预防。抗凝剂剂量需要实验室监测。实验室控制的国际标准化系统是必要的。本文描述了一种基于提供标准化组织凝血活酶提取物（英国比较凝血活酶）的系统。该系统在包括一组有代表性的意大利医院在内的70个国家的实验室中使用，目前被推荐作为国际参考制剂。
