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职业性和实验性接触中苯乙烯的神经毒性

Neurotoxicity of styrene in occupational and experimental exposure.

作者信息

Seppäläinen A M

出版信息

Scand J Work Environ Health. 1978;4 Suppl 2:181-3.

PMID:734403
Abstract

Occupational styrene exposure caused an increased frequency of abnormal electroencephalograms which correlated to degree of exposure. No dose-response relationship could be shown concerning a slowing of nerve conduction velocities in workers exposed to styrene. Experimental exposure of rats to 300 ppm of styrene caused a transient increase in the nerve conduction velocity in 6 weeks, but in a comparison to control rats no difference was found in measurements performed on rats exposed for 8 and 11 weeks.

摘要

职业性接触苯乙烯会导致异常脑电图的频率增加,且这与接触程度相关。对于接触苯乙烯的工人,未发现神经传导速度减慢存在剂量-反应关系。将大鼠实验性暴露于300 ppm的苯乙烯中6周会导致神经传导速度短暂增加,但与对照大鼠相比,在暴露8周和11周的大鼠身上进行的测量未发现差异。

相似文献

1
Neurotoxicity of styrene in occupational and experimental exposure.职业性和实验性接触中苯乙烯的神经毒性
Scand J Work Environ Health. 1978;4 Suppl 2:181-3.
2
Neurophysiological observations after chronic styrene exposure.慢性苯乙烯暴露后的神经生理学观察。
Scand J Work Environ Health. 1978;4 Suppl 2:184-94.
3
Study of urinary mandelic acid concentration and peripheral nerve conduction among styrene workers.苯乙烯作业工人尿中扁桃酸浓度与周围神经传导的研究。
Am J Ind Med. 1996 Jul;30(1):41-7. doi: 10.1002/(SICI)1097-0274(199607)30:1<41::AID-AJIM7>3.0.CO;2-V.
4
Health status of styrene-polystyrene polymerization workers.苯乙烯 - 聚苯乙烯聚合工人的健康状况。
Scand J Work Environ Health. 1978;4 Suppl 2:220-6.
5
A critical review of the neurotoxicity of styrene in humans.
Vet Hum Toxicol. 1993 Dec;35(6):516-20.
6
Neurotoxic effects of styrene: further evidence.苯乙烯的神经毒性作用:更多证据
Br J Ind Med. 1990 Jan;47(1):29-37. doi: 10.1136/oem.47.1.29.
7
Styrene, its experimental and clinical toxicology. A review.苯乙烯的实验与临床毒理学。综述。
Scand J Work Environ Health. 1978;4 Suppl 2:104-13.
8
Alcohol consumption and tolerance of workers exposed to styrene in relation to level of exposure and psychological symptoms and signs.与接触水平、心理症状和体征相关的接触苯乙烯工人的酒精消费与耐受性
Scand J Work Environ Health. 1978;4 Suppl 2:196-9.
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Clinical and experimental research into the pathogenesis of toxic effect of styrene. VII. Appraisal of the nervous system in the workers exposed to styrene.
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Dose-dependent neurophysiological and biochemical effects of prolonged vinyltoluene vapor inhalation in rat.大鼠长期吸入乙烯基甲苯蒸气的剂量依赖性神经生理和生化效应。
Neurotoxicology. 1982 Jul;3(1):36-43.

引用本文的文献

1
Biological monitoring of styrene in the reinforced plastics industry in Emilia Romagna, Italy.意大利艾米利亚-罗马涅地区增强塑料行业中苯乙烯的生物监测。
Int Arch Occup Environ Health. 1993;65(2):89-95. doi: 10.1007/BF00405725.
2
Neurotoxic effects of styrene: further evidence.苯乙烯的神经毒性作用:更多证据
Br J Ind Med. 1990 Jan;47(1):29-37. doi: 10.1136/oem.47.1.29.