Alexander A M, Wood J B
J Clin Hosp Pharm. 1981 Mar;6(1):57-61. doi: 10.1111/j.1365-2710.1981.tb00887.x.
Analysis of the prescribing of systemic anti-bacterial drugs in the medical wards of a district general hospital from April 1975 to March 1979 showed that 26% of patients received these drugs and that ampicillin, amoxycillin and cotrimoxazole were prescribed much more frequently than other agents. During this time, there were considerable changes in prescribing habits, with increases noted in amoxycillin, flucloxacillin and metronidazole. These changes were paralleled by decreases in ampicillin, cloxacillin and clindamycin usage.
对一家地区综合医院1975年4月至1979年3月内科病房全身用抗菌药物处方情况的分析表明,26%的患者接受了这些药物治疗,氨苄西林、阿莫西林和复方新诺明的处方频率远高于其他药物。在此期间,处方习惯发生了显著变化,阿莫西林、氟氯西林和甲硝唑的使用量增加。氨苄西林、氯唑西林和克林霉素的使用量则相应减少。