Wyatt T D, Passmore C M, Morrow N C, Reilly P M
Mater Infirmorum Hospital, Belfast.
BMJ. 1990 Feb 17;300(6722):441-4. doi: 10.1136/bmj.300.6722.441.
To see whether changes in prescribing of oral antibacterials in Northern Ireland show the need for a community antibiotics policy.
Analysis of prescribing totals for several oral antibiotics obtained retrospectively from the prescription pricing bureau for the years 1983-7.
Audit of anti-infective prescribing in general practice in Northern Ireland over five years.
Respective usage of agents defined as "common" and "occasional" in 1983.
There was a gradual decrease in the relative use of common agents from 82% of the total in 1983 to 77% in 1987 together with a complementary increase in the use of occasional agents from 5% to 10%. Pronounced changes were noted in the use of amoxycillin, ampicillin, erythromycin, minocycline, doxycycline, and amoxycillin-clavulanic acid.
Though this survey found reasonably conservative prescribing, the trend towards increased use of occasional agents has both clinical and cost implications which could be addressed by the use of a prescribing formulary.
了解北爱尔兰口服抗菌药物处方的变化是否表明需要制定一项社区抗生素政策。
对1983 - 1987年从处方定价局回顾性获取的几种口服抗生素的处方总量进行分析。
对北爱尔兰全科医疗中五年抗感染药物处方的审计。
1983年定义为“常用”和“偶尔使用”的药物各自的使用情况。
常用药物的相对使用量从1983年占总量的82%逐渐降至1987年的77%,同时偶尔使用药物的使用量相应地从5%增至10%。阿莫西林、氨苄西林、红霉素、米诺环素、多西环素和阿莫西林 - 克拉维酸的使用出现了显著变化。
尽管本次调查发现处方较为保守,但偶尔使用药物使用量增加的趋势在临床和成本方面都有影响,可通过使用处方集来解决。