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古古勒树脂(没药树)和大蒜(蒜)对犬(家犬)及猴(叶猴)的降血脂活性

Hypolipidemic activity of guggal resin (Commiphora mukul) and garlic (Alium sativum linn.) in dogs (Canis familiaris) and monkeys (Presbytis entellus entellus Dufresne).

作者信息

Dixit V P, Joshi S, Sinha R, Bharvava S K, Varma M

出版信息

Biochem Exp Biol. 1980;16(4):421-4.

PMID:7346059
Abstract
  1. The identification of cholesterol as a constituent in the genesis of coronary artery disease in man and experimental animals are well documented. 2. The hypolipidemic effects of Commiphora mukul (guggulu) and Alium sativum (Garlic powder) were screened in dog and Presbytis monkeys. 3. Progressive decrease in the mean values of cholesterol, triglycerides and phospholipids were conspicuous for forty eight hours following the administration of guggulu/garlic powder. 4. 25 mg/kg body weight garlic powder was more effective in lowering the serum cholesterol and triglycerides as compared with that of guggulu. 5. A comparative hypolipidemic action of the two compounds is discussed.
摘要
  1. 胆固醇作为人类和实验动物冠状动脉疾病发病机制中的一种成分已得到充分证实。2. 在犬和豚尾猴中筛选了没药(古古勒)和大蒜粉的降血脂作用。3. 服用古古勒/大蒜粉后48小时,胆固醇、甘油三酯和磷脂的平均值显著逐渐下降。4. 与古古勒相比,25毫克/千克体重的大蒜粉在降低血清胆固醇和甘油三酯方面更有效。5. 讨论了这两种化合物的比较降血脂作用。

相似文献

1
Hypolipidemic activity of guggal resin (Commiphora mukul) and garlic (Alium sativum linn.) in dogs (Canis familiaris) and monkeys (Presbytis entellus entellus Dufresne).古古勒树脂(没药树)和大蒜(蒜)对犬(家犬)及猴(叶猴)的降血脂活性
Biochem Exp Biol. 1980;16(4):421-4.
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Hypolipidemic effect of garlic protein substituted for casein in diet of rats compared to those of garlic oil.与大蒜油相比,大蒜蛋白替代大鼠饮食中酪蛋白的降血脂作用。
Indian J Exp Biol. 1996 Apr;34(4):337-40.
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Effect of allicin from garlic powder on serum lipids and blood pressure in rats fed with a high cholesterol diet.大蒜粉中蒜素对高胆固醇饮食喂养大鼠血脂和血压的影响。
Prostaglandins Leukot Essent Fatty Acids. 2000 Apr;62(4):253-9. doi: 10.1054/plef.2000.0152.
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Beneficial effects of Allium sativum, Allium cepa and Commiphora mukul on experimental hyperlipidemia and atherosclerosis--a comparative evaluation.大蒜、洋葱和没药对实验性高脂血症和动脉粥样硬化的有益作用——一项比较评估。
J Postgrad Med. 1991 Jul;37(3):132-5.
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Effect of the dried powder extract, water soluble of garlic (Allium sativum) on cholesterol, triglyceride and high density lipoprotein in the blood.
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Comparative hypolipidaemic effectiveness of gum guggulu (Commiphora mukul) fraction 'A', ethyl-P-chlorophenoxyisobutyrate and Ciba-13437-Su.
Indian J Med Res. 1971 Oct;59(10):1621-32.
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Hypolipidemic activity of tincture of Crataegus in rats.山楂酊对大鼠的降血脂活性
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Biochemical studies on combined effects of garlic (Allium sativum Linn) and ginger (Zingiber officinale Rosc) in albino rats.大蒜(蒜)和生姜(姜科姜属)对白化大鼠联合作用的生化研究。
Indian J Exp Biol. 1997 Aug;35(8):841-3.
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Biochemical effects of garlic protein on lipid metabolism in alcohol fed rats.大蒜蛋白对酒精喂养大鼠脂质代谢的生化作用。
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Effect of bilateral vasectomy on liver function in langur monkeys (Presbytis entellus entellus Dufresne).双侧输精管结扎对叶猴(食蟹猴指名亚种)肝功能的影响。
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引用本文的文献

1
Googling the Guggul (Commiphora and Boswellia) for Prevention of Chronic Diseases.搜索古古勒(没药属和乳香属)用于预防慢性病
Front Pharmacol. 2018 Aug 6;9:686. doi: 10.3389/fphar.2018.00686. eCollection 2018.
2
Guggulsterone-mediated enhancement of radiosensitivity in human tumor cell lines.古柯二醇介导的人肿瘤细胞系放射敏感性增强。
Front Oncol. 2011 Jul 21;1:19. doi: 10.3389/fonc.2011.00019. eCollection 2011.