Bille B
Cephalalgia. 1981 Jun;1(2):71-5. doi: 10.1111/j.1468-2982.1981.tb00012.x.
In 1955 a population study in Uppsala comprising about 9,000 school children showed that migraine increased from 1.4% at the age of seven to 5.3% at fifteen. With increasing age there was an increasing predominance of girls. A matched comparison between 73 children with more pronounced migraine and 73 control children showed a greater tendency in the migraine group to abdominal pain, motion sickness, sleep disturbance and orthostatic symptoms. In a longitudinal study lasting 23 years the 73 migraine children were followed-up until all were over 30 years of age. During puberty and as young adults 62% were free from migraine for at least two years. Of these, 22% again suffered migraine regularly. Thus, 60% had migraine attacks at 30. Girls seem to have a greater relapse rate than boys. Most of the girls with classical migraine were headache free during pregnancy. Every third family with one parent belonging to the migraine group and with children over four years of age had one child with migraine symptoms. Migraine seems to be more frequently inherited via the mother, and to girls.
1955年，在乌普萨拉进行的一项涵盖约9000名学童的人口研究表明，偏头痛的发病率从7岁时的1.4%上升至15岁时的5.3%。随着年龄增长，女孩的患病率优势愈发明显。对73名偏头痛症状更明显的儿童与73名对照儿童进行匹配比较后发现，偏头痛组的儿童出现腹痛、晕动病、睡眠障碍和直立性症状的倾向更大。在一项为期23年的纵向研究中，对这73名偏头痛儿童进行了跟踪随访，直至他们全部超过30岁。在青春期和成年早期，62%的人至少有两年没有偏头痛发作。其中，22%的人又再次经常遭受偏头痛困扰。因此，60%的人在30岁时患有偏头痛。女孩的复发率似乎比男孩更高。大多数患有典型偏头痛的女孩在怀孕期间没有头痛症状。在父母一方属于偏头痛组且有4岁以上孩子的家庭中，每三个家庭就有一个孩子有偏头痛症状。偏头痛似乎更常通过母亲遗传给女孩。
