Shoji K, Watanabe H, Goto Y, Yamada N
Tohoku J Exp Med. 1978 Nov;126(3):289-93. doi: 10.1620/tjem.126.289.
The study was made to ascertain whether the radiographs of the mandible of patients with familial polyposis of the colon show osteomas. Orthopantomography of the mandible was taken in 10 cases of familial polyposis of the colon and 6 cases of the unaffected family members. And radiographic and histological studies were performed in another autopsied case. As a result, radiographic studies revealed sclerotic masses of the mandible in 10 of the 11 cases. In some cases, the changes were also found in the maxilla. The number of sclerotic masses ranged from 2 to 11, and they were associated with odontomas in 2 cases and impacted teeth in one case. Two of the 6 unaffected family members were found to have one or two sclerotic masses. At autopsy of a case died of cancer of the sigmoid colon, a radiographic study of the excised mandible revealed 11 sclerotic masses measuring 5 mm in diameter each, as well as one impacted tooth. A bucco-lingual cross action through the mandible in the canine area revealed central osteomas. Histological examination showed the osteomas were composed primarily of mature, lamellar bony tissue.
本研究旨在确定结肠家族性息肉病患者的下颌骨X线片是否显示骨瘤。对10例结肠家族性息肉病患者及6例未患病的家庭成员进行了下颌骨全景X线摄影。并对另一具尸体解剖病例进行了影像学和组织学研究。结果，影像学研究显示，11例中有10例下颌骨出现硬化性肿块。在某些病例中，上颌骨也发现了变化。硬化性肿块的数量从2个到11个不等，其中2例与牙瘤有关，1例与阻生牙有关。6例未患病的家庭成员中有2例发现有1个或2个硬化性肿块。在1例死于乙状结肠癌的病例尸检中，对切除的下颌骨进行影像学研究发现有11个直径为5毫米的硬化性肿块，以及1颗阻生牙。在犬齿区对下颌骨进行颊舌向横断切片显示为中央型骨瘤。组织学检查显示，骨瘤主要由成熟的板层骨组织构成。
