Utsunomiya J, Nakamura T
Br J Surg. 1975 Jan;62(1):45-51. doi: 10.1002/bjs.1800620111.
Characteristic radio-opaque lesions were detected in the manibular bone, most clearly on the panoramic X-ray, in 27 or 93-2 per cent out of 29 cases in 15 families with familial polyposis coli, including 21 cases without Gardner's stigmata, 7 cases with the incomplete syndrome and 1 with the complete syndrome. Only 3 out of 19 members of these families who were free from polposis had radio-opaque jaw lesions. The cases with polyposis of other types also showed a negative result. The radiological diagnosis suggested that the lesions were of the character of endosteoma. Our observation is considered to be significant evidence in the understanding of the pathogenesis of Gardner's syndrome as well as a useful method of the early detection of carriers in the polyposis family.
在15个患有家族性结肠息肉病的家庭中的29例患者中，有27例（占93.2%）在下颌骨发现了典型的不透X线病变，在全景X线片上最为明显，其中包括21例无Gardner综合征体征的患者、7例不完全综合征患者和1例完全综合征患者。在这些家族中，19名无息肉病的成员中只有3人有不透X线的颌骨病变。其他类型息肉病的病例也显示为阴性结果。放射学诊断表明这些病变具有骨内膜瘤的特征。我们的观察被认为是理解Gardner综合征发病机制的重要证据，也是在息肉病家族中早期发现携带者的一种有用方法。
