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一种药物定性和定量测量的非侵入性方法。

A non-invasive method of qualitative and quantitative measurement of drugs.

作者信息

Westerman S T, Gilbert L M

出版信息

Laryngoscope. 1981 Sep;91(9 Pt 1):1536-47.

PMID:7346697
Abstract

Methods for quick qualitative and quantitative evaluation of drug intake are needed, especially during emergency situations such as drug overdose and alcohol intoxication. The electronystagmograph was used in an attempt to develop a non-invasive method for identification of drug intake, and to study the effects of alcohol and other drugs on the vestibular system. Results of the study reveal that alcohol, diazepam, opiates, barbiturates, cocaine, marijuana, and hallucinogenic drugs produce a characteristic printout pattern which can be evaluated qualitatively. This method is a practical, non-invasive, objective procedure that provides rapid assessment of quality of drug intake. Its potential uses are extensive, including such possibilities as evaluation of drug intake in emergency drug overdose situations, monitoring anesthesia during surgery, evaluating drug intake in women about to deliver, (as well as the effects on the newborn), and determining whether or not persons who are being tested on a polygraph are under the influence of drugs.

摘要

需要有快速定性和定量评估药物摄入情况的方法,尤其是在药物过量和酒精中毒等紧急情况下。曾尝试使用眼震电图来开发一种用于识别药物摄入的非侵入性方法,并研究酒精和其他药物对前庭系统的影响。研究结果表明,酒精、地西泮、阿片类药物、巴比妥类药物、可卡因、大麻和致幻药物会产生一种可定性评估的特征性打印输出模式。该方法是一种实用、非侵入性的客观程序,可快速评估药物摄入的情况。其潜在用途广泛,包括在紧急药物过量情况下评估药物摄入、手术期间监测麻醉、评估即将分娩的妇女的药物摄入情况(以及对新生儿的影响),以及确定接受测谎仪测试的人是否受到药物影响。

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