Paes I B, da Silveira G M
Arq Gastroenterol. 1981 Oct-Dec;18(4):152-5.
Twenty patients with duodenal ulcer, clinically diagnosed, were treated. Radiologic and endoscopic controls were carried out. Following a random scheme, a group of ten patients was treated with conventional cimetidine and a group of ten with cimetidine of sustained release. The authors consider that cimetidine of sustained release offers the advantage of minor doses and major facility of administration. Similar results were therapeutically obtained.