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[心脏和肝脏发育及衰老过程中细胞细胞器的变化]

[Changes of cell organelles in the developmental and aging process of heart and liver].

作者信息

David H

出版信息

Gegenbaurs Morphol Jahrb. 1981;127(4):564-73.

PMID:7347713
Abstract

A systematic comparative investigation into the qualitative and quantitative ultrastructure of rat hearts and livers during postnatal development and ageing shows that there are similar and opposing changes within the hepatocytes and cardiocytes and their components. These processes are represented in male rats from birth up to the age of 27 months. The morphometrical examinations include cytoplasm, lipids, glycogen, mitochondria as well as primary and secondary lysosomes. The development of organs constitutes a dialectical unity of continuous and discontinuous processes within the cells characterized by degenerative as well as regenerative and synthetic processes. This results in transformation of the structural organization of the cells during the whole life.

摘要

一项对出生后发育和衰老过程中大鼠心脏和肝脏的定性和定量超微结构进行的系统比较研究表明,肝细胞和心肌细胞及其组成部分存在相似和相反的变化。这些过程在雄性大鼠中从出生到27个月龄都有体现。形态计量学检查包括细胞质、脂质、糖原、线粒体以及初级和次级溶酶体。器官的发育构成了细胞内连续和不连续过程的辩证统一,其特征为退化以及再生和合成过程。这导致细胞的结构组织在整个生命过程中发生转变。

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