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[活检材料中恶性非霍奇金淋巴瘤的发生率。一项回顾性研究]

[Frequency of malignant non-Hodgkin's lymphomas in biopsy material. A retrospective study].

作者信息

Rüdiger K D, Wöckel W

出版信息

Zentralbl Allg Pathol. 1981;125(3):191-8.

PMID:7347962
Abstract

The biopsy material of the Institute of Pathology of the Medical Academy of Erfurt, GDR, from January 1967 to February 1978 has been reinvestigated for malignant non-Hodgkin's lymphomas which were reclassified according to the Kiel classification (Gérard-Marchant et al. 1974). We observed 122 (72.6%) low grade malignant lymphomas and 46 (27.4%) high grade malignant lymphomas. 17 cases remained unclassifiable. The median age ranged between 47.6 years (lymphoblastic malignant lymphoma) and 65.8 years (centrocytic malignant lymphoma). The sex ratio shows a predominance of males for all types of low grade malignant lymphomas. Only the immunoblastic malignant lymphoma in the group of high grade malignant lymphomas has a predominance in females. The survival of patients with high grade malignant lymphomas shows a good correspondence to the data given in the literature, whereas patients suffering from low grade malignant lymphomas have a distinctly worse prognosis in our material in comparison to literature data.

摘要

对民主德国爱尔福特医学院病理研究所1967年1月至1978年2月间的活检材料进行了重新研究,以查找恶性非霍奇金淋巴瘤,并根据基尔分类法(热拉尔 - 马尔尚等人,1974年)重新分类。我们观察到122例(72.6%)低级别恶性淋巴瘤和46例(27.4%)高级别恶性淋巴瘤。17例仍无法分类。中位年龄在47.6岁(淋巴母细胞性恶性淋巴瘤)至65.8岁(中心细胞性恶性淋巴瘤)之间。性别比显示,所有类型的低级别恶性淋巴瘤中男性占主导。只有高级别恶性淋巴瘤组中的免疫母细胞性恶性淋巴瘤女性占主导。高级别恶性淋巴瘤患者的生存率与文献中的数据吻合良好,而在我们的材料中,低级别恶性淋巴瘤患者的预后与文献数据相比明显更差。

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