Lunn R J, Savageau M M, Beatty W W, Gerst J W, Staton R D, Brumback R A
Biol Psychiatry. 1981 Dec;16(12):1163-75.
The anesthetic agents methohexital (Brevital), Innovar, and ketamine (Ketaject) were examined for their effect on seizure duration following electroconvulsive stimulation in a rat model of electroconvulsive therapy (ECT). Compared to unanesthetized control animals, methohexital anesthesia shortened seizure duration by 42%, ketamine anesthesia tended to increase seizure duration, and Innovar anesthesia had no effect on duration of seizures.