McClugage S G, Holmstedt J O, Malloy R B
J Biomed Mater Res. 1980 Sep;14(5):631-8. doi: 10.1002/jbm.820140509.
An in vivo model has been designed to study the acute response of exposed or unexposed dental pulp to the topical application of various biomaterials. This model permits sequential microscopic observations of the microvascular system of dental pulp before and after application of pulp capping agents, cementing agents, or cavity liners. The use of this experimental model provides useful information related to the tolerability of dental pulp to various biomaterials used in dentistry. Furthermore, this model serves as a useful supplement to more traditional long term methods for evaluating the biocompatability of dental materials.
已设计出一种体内模型，用于研究暴露或未暴露的牙髓对各种生物材料局部应用的急性反应。该模型允许在应用牙髓盖髓剂、粘结剂或洞衬剂之前和之后对牙髓微血管系统进行连续的显微镜观察。使用该实验模型可提供与牙髓对牙科中使用的各种生物材料的耐受性相关的有用信息。此外，该模型可作为评估牙科材料生物相容性的更传统长期方法的有用补充。
