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可弯曲纤维支气管镜在淋巴瘤肺部并发症诊断中的应用

Flexible fiberoptic bronchoscopy in the diagnosis of pulmonary complication of lymphoma.

作者信息

Chuang M T, Teirstein A S, Gribetz A R, Berman L B, Nieburgs H E

出版信息

Cancer Detect Prev. 1981;4(1-4):347-50.

PMID:7349796
Abstract

Patients with known lymphoma frequently present with pulmonary abnormalities that require prompt diagnosis. The usual chest radiograph and bacteriologic studies often fail to be of diagnostic value. Since February 1973, we have performed flexible fiberoptic bronchoscopies on 76 patients with Hodgkin and non-Hodgkin lymphoma who presented with pulmonary abnormalities. Biopsy specimens revealed lymphoma in 21 of these 76 patients, pneumocystic carinii infection in six, aspergillus infection in three, and cryptococcus, herpes simplex, and squamous cell carcinoma, respectively, in the remaining three. In all, specific diagnosis was obtained in 33 patients (43%). One death from bleeding occurred in a patient with marked thrombocytopenia and respiratory failure. Flexible bronchoscopy is recommended as a valuable, relatively risk-free procedure in the diagnosis of the pulmonary manifestations, or complications, of lymphoma.

摘要

已知患有淋巴瘤的患者经常出现需要及时诊断的肺部异常情况。常规胸部X光片和细菌学检查往往没有诊断价值。自1973年2月以来,我们对76例患有霍奇金淋巴瘤和非霍奇金淋巴瘤且出现肺部异常的患者进行了纤维支气管镜检查。活检标本显示,这76例患者中有21例为淋巴瘤,6例为卡氏肺孢子虫感染,3例为曲霉菌感染,其余3例分别为隐球菌、单纯疱疹和鳞状细胞癌。总共33例患者(43%)获得了明确诊断。1例血小板显著减少并伴有呼吸衰竭的患者死于出血。对于淋巴瘤肺部表现或并发症的诊断,纤维支气管镜检查被推荐为一种有价值且相对无风险的检查方法。

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