Roth A, Lang S, Kolarić K
Cancer Detect Prev. 1981;4(1-4):351-9.
In Yugoslavia, esophageal cancer is the fourth most frequent malignant disease of the gastrointestinal tract, after stomach cancer, rectum, and colon cancer. Incidence of esophageal cancer in Croatia in 1975 was 6.0 per 100,000 population for males, and considerably less for females with 1.4 per 100,000 population. There is not a statistically significant difference in the incidence of esophageal cancer in the different regions within Croatia. During the period from March 1973 to April 1980 at the Central Institute for Tumors and Allied Diseases in Zagreb, esophagoscopy was performed on 179 patients with esophageal tumors. Test results of 170 patients was 60.4 years (male 60.0, female 62.4). The authors present the analyses of histopathologic types of tumors. In 79.4% of patients (135/170) squamous cell carcinoma was found. In 69 patients histologic findings were compared with cytology. In six patients, only the cytological examinations were positive. Furthermore, the localizations of tumors in the esophagus were analyzed, and in 53.6% of patients (91/170) tumor was localized in the middle third of the esophagus. In almost all cases the disease was advanced and inoperable. Smoking and alcoholism were analyzed as potential etiological factors. The authors consider that esophagoscopy could be a valuable method in the early detection of esophageal carcinoma in the high risk group of the population (men over 50 years of age who are heavy alcoholics and smokers).
在南斯拉夫，食管癌是胃肠道第四大常见恶性疾病，仅次于胃癌、直肠癌和结肠癌。1975年，克罗地亚男性食管癌发病率为每10万人中有6.0例，女性发病率则低得多，为每10万人中有1.4例。克罗地亚不同地区的食管癌发病率没有统计学上的显著差异。1973年3月至1980年4月期间，在萨格勒布的中央肿瘤及相关疾病研究所，对179例食管肿瘤患者进行了食管镜检查。170例患者的测试结果显示平均年龄为60.4岁（男性60.0岁，女性62.4岁）。作者展示了对肿瘤组织病理学类型的分析。在79.4%的患者（135/170）中发现了鳞状细胞癌。对69例患者的组织学检查结果与细胞学检查结果进行了比较。在6例患者中，仅细胞学检查呈阳性。此外，还分析了食管肿瘤的位置，53.6%的患者（91/170）肿瘤位于食管中段。几乎所有病例的疾病都已进展到无法手术的程度。对吸烟和酗酒作为潜在病因进行了分析。作者认为，食管镜检查可能是在高危人群（50岁以上重度酗酒和吸烟的男性）中早期发现食管癌的一种有价值的方法。
