分流感染治疗期间脑脊液中的抗生素水平。
Cerebrospinal fluid antibiotic levels during treatment of shunt infections.
作者信息
Wald S L, McLaurin R L
出版信息
J Neurosurg. 1980 Jan;52(1):41-6. doi: 10.3171/jns.1980.52.1.0041.
PMID:7350279
Abstract
Twenty patients with documented cerebrospinal fluid shunt infections were treated with daily intraventricular injections of methicillin, cephalothin, or gentamicin without removal of the shunt or external ventricular drainage. Periodic determinations of intraventricular antibiotic concentration revealed significant levels in relation to the established minimum inhibitory concentration in all cases.
摘要
20例有脑脊液分流感染记录的患者接受了每日脑室内注射甲氧西林、头孢噻吩或庆大霉素的治疗，未移除分流装置或进行脑室外引流。定期测定脑室内抗生素浓度显示，在所有病例中，相对于既定的最低抑菌浓度，抗生素浓度均达到显著水平。
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