生长激素和氧雄龙单独及联合使用对X染色体异常女孩生长速率的影响。
Effect of growth hormone and oxandrolone singly and together on growth rate in girls with X chromosome abnormalities.
作者信息
Rudman D, Goldsmith M, Kutner M, Blackston D
出版信息
J Pediatr. 1980 Jan;96(1):132-5. doi: 10.1016/s0022-3476(80)80349-0.
The linear growth effects of oxandrolone, human growth hormone, and Ox + hGH were compared in six girls, age 11 to 15 years, with X chromosome abnormalities (three with X,O karyotype, three with Turner syndrome variants). Over six successive three-month periods, the patient received either no treatment, Ox, hGH, or Ox + hGH. The data demonstrate a significant (P less than 0.001) synergistic effect between Ox and hGH in stimulating linear growth in Turner syndrome and its variants.
对6名年龄在11至15岁、患有X染色体异常（3名X,O核型，3名特纳综合征变异型）的女孩，比较了氧雄龙、人生长激素以及氧雄龙+人生长激素的线性生长效应。在连续六个为期三个月的时间段里，患者分别接受无治疗、氧雄龙、人生长激素或氧雄龙+人生长激素治疗。数据表明，在特纳综合征及其变异型中，氧雄龙和人生长激素在刺激线性生长方面具有显著的（P<0.001）协同效应。
Zotero 插件