生长激素用于身材矮小、生长缓慢的儿童以及患有特纳综合征的儿童。
Growth hormone in short, slowly growing children and those with Turner's syndrome.
作者信息
Buchanan C R, Law C M, Milner R D
机构信息
Institute of Child Health, London.
出版信息
Arch Dis Child. 1987 Sep;62(9):912-6. doi: 10.1136/adc.62.9.912.
Abstract
Results of an aborted placebo controlled trial of treatment with human pituitary growth hormone in children with Turner's syndrome and short, slowly growing children are reported. One child in each group had a considerable reduction in growth rate standard deviation score while taking growth hormone. The remaining eight patients with Turner's syndrome and 10 short, slowly growing patients who received growth hormone showed mean rises in growth rate of greater than two standard deviation scores. Neither placebo group showed a mean increase in growth rate standard deviation score. These differences were significant.
摘要
报告了一项针对特纳综合征儿童及身材矮小、生长缓慢儿童的人垂体生长激素治疗的安慰剂对照试验中止后的结果。每组中有一名儿童在服用生长激素期间生长速率标准差评分有显著降低。其余8名特纳综合征患者和10名身材矮小、生长缓慢且接受生长激素治疗的患者生长速率平均升高超过两个标准差评分。两个安慰剂组的生长速率标准差评分均未出现平均增加。这些差异具有显著性。
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