Sung R J, Styperek J L, Castellanos A
Am J Cardiol. 1980 Jan;45(1):72-8. doi: 10.1016/0002-9149(80)90222-2.
In an attempt to prevent recurrent reentrant supraventricular tachycardia, an experimentally designed new pacemaker has been developed. The pacemaker, when connected to both atrial and ventricular electrodes, is capable of sensing either an atrial or ventricular signal and, in turn, triggers simultaneous atrioventricular A-V) stimulation. Efficacy of this pacemake was tested in four patients with recurrent paroxysmal A-V nodal reentrant tachycardia during electrophysiologic studies. After connection of the electrodes to the new pacemaker, all atrial or ventricular premature stimuli elicited simultaneous A-V stimulation with resultant impulse collision in the A-V junction. Consequently, the reentrant tachycardia zone was completely abolished in all patients. This study has thus demonstrated the clinical feasibility of simultaneous A-V pacing to abolish the supraventricular tachycardia zone in man.
为了预防复发性折返性室上性心动过速,已研发出一种经实验设计的新型起搏器。该起搏器连接心房和心室电极后,能够感知心房或心室信号,进而触发同时性房室(A-V)刺激。在电生理研究中,对4例复发性阵发性房室结折返性心动过速患者测试了这种起搏器的疗效。将电极连接到新型起搏器后,所有心房或心室早搏刺激均引发同时性A-V刺激,导致冲动在房室交界区发生碰撞。因此,所有患者的折返性心动过速区域均被完全消除。这项研究从而证明了同时性房室起搏消除人体室上性心动过速区域的临床可行性。