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患有囊性纤维化的新生儿胎粪异常的发生率。

Incidence of meconium abnormalities in newborn infants with cystic fibrosis.

作者信息

Rosenstein B J, Langbaum T S

出版信息

Am J Dis Child. 1980 Jan;134(1):72-3. doi: 10.1001/archpedi.1980.02130130054016.

DOI:10.1001/archpedi.1980.02130130054016
PMID:7350790
Abstract

Review of the newborn nursery notes of 87 infants who had cystic fibrosis without meconium ileus (MI) indicated that 12 of them had clinical features consistent with the meconium plug syndrome (MPS). This high incidence of meconium abnormalities suggests that MI and the MPS probably represent different gradations of the same underlying pathologic abnormality. The findings further suggest that a quantitative pilocarpine iontophoresis sweat test be performed in every newborn infant with any type of meconium abnormality, including the spontaneous passage of meconium plugs.

摘要

对87例患有无胎粪性肠梗阻(MI)的囊性纤维化婴儿的新生儿护理记录进行回顾发现,其中12例具有与胎粪性栓子综合征(MPS)相符的临床特征。胎粪异常的高发生率表明,MI和MPS可能代表同一潜在病理异常的不同程度。这些发现进一步表明,应对每例有任何类型胎粪异常(包括胎粪栓子自然排出)的新生儿进行毛果芸香碱离子电渗汗液定量试验。

相似文献

1
Incidence of meconium abnormalities in newborn infants with cystic fibrosis.患有囊性纤维化的新生儿胎粪异常的发生率。
Am J Dis Child. 1980 Jan;134(1):72-3. doi: 10.1001/archpedi.1980.02130130054016.
2
Cystic fibrosis presenting with the meconium plug syndrome.以胎粪性肠梗阻综合征表现的囊性纤维化
Am J Dis Child. 1978 Feb;132(2):167-9. doi: 10.1001/archpedi.1978.02120270065014.
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The spectrum of meconium disease in infancy.婴儿期胎粪疾病的谱系
J Pediatr Surg. 1982 Oct;17(5):479-81. doi: 10.1016/s0022-3468(82)80093-6.
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Gastrointestinal manifestations of cystic fibrosis.囊性纤维化的胃肠道表现。
Pediatr Clin North Am. 1975 Nov;22(4):787-805. doi: 10.1016/s0031-3955(16)33208-4.
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The impact of cystic fibrosis on neonatal intestinal obstruction: the need for prenatal/neonatal screening.囊性纤维化对新生儿肠梗阻的影响:产前/新生儿筛查的必要性。
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Meconium plug obstruction.胎粪栓梗阻
Pediatr Surg Int. 2004 Feb;20(2):108-10. doi: 10.1007/s00383-003-1098-y. Epub 2004 Feb 4.
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Protein in meconium from meconium ileus.胎粪性肠梗阻患儿胎粪中的蛋白质。
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Meconium ileus in newborns with cystic fibrosis - results of treatment in the group of patients operated on in the years 2000-2014.患有囊性纤维化的新生儿胎粪性肠梗阻——2000年至2014年接受手术治疗患者组的治疗结果
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[Notes to the article Nekl R., Mockóva, A., Bierhanzlová, J., Kutilová J. "Meconium Ileus as a first symptom of cystic fibrosis in a newborn"].
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[Mucoviscidosis (cystic fibrosis)].[黏液黏稠症(囊性纤维化)]
Internist (Berl). 1976 Jul;17(7):336-41.

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Meconium ileus caused by mutations in GUCY2C, encoding the CFTR-activating guanylate cyclase 2C.
由 GUCY2C 基因突变引起的胎粪性肠梗阻,该基因编码 CFTR 激活型鸟苷酸环化酶 2C。
Am J Hum Genet. 2012 May 4;90(5):893-9. doi: 10.1016/j.ajhg.2012.03.022. Epub 2012 Apr 19.
4
Meconium plug obstruction.胎粪栓梗阻
Pediatr Surg Int. 2004 Feb;20(2):108-10. doi: 10.1007/s00383-003-1098-y. Epub 2004 Feb 4.
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Intestinal obstruction and cystic fibrosis: antenatal ultrasound appearance.肠梗阻与囊性纤维化:产前超声表现
J Med Genet. 1983 Jun;20(3):229-30. doi: 10.1136/jmg.20.3.229.
6
The chest radiograph in cystic fibrosis in children and the role of other radiological techniques.儿童囊性纤维化的胸部X线片及其他放射学技术的作用。
J R Soc Med. 1987;80 Suppl 15(Suppl 15):38-46.
7
Meconium ileus in the absence of cystic fibrosis.无囊性纤维化的胎粪性肠梗阻
Arch Dis Child. 1992 Oct;67(10 Spec No):1204-6. doi: 10.1136/adc.67.10_spec_no.1204.