Stahl S M, Johnson K P, Malamud N
Arch Neurol. 1980 Jan;37(1):25-9. doi: 10.1001/archneur.1980.00500500055007.
Three cases of brain-stem vascular malformation with progressive and fluctuating clinical courses of longer than one year were studied. One patient with a rare brain-stem arteriovenous malformation lived for 20 years with symptoms notably similar to those of multiple sclerosis (MS). One case each of cavernous hemangioma and capillary telangiectasis are also described. The clinical, roentgenographic, and pathologic features of these three cases plus 18 other cases of brain-stem vascular malformations from the literature, with progressive or intermittent clinical courses and with survival of longer than one year from the onset of symptoms, are reviewed. Since nearly all of these cases were once mistakenly diagnosed as MS, a diagnostic approach is proposed to help distinguish brain-stem vascular malformations from MS prior to an obvious subarachnoid hemorrhage.
对3例脑干血管畸形患者进行了研究，其临床病程呈进行性且有波动，持续时间超过1年。1例患有罕见脑干动静脉畸形的患者存活了20年，其症状与多发性硬化症（MS）显著相似。还描述了1例海绵状血管瘤和1例毛细血管扩张症。回顾了这3例病例以及文献中另外18例脑干血管畸形病例的临床、影像学和病理学特征，这些病例临床病程呈进行性或间歇性，自症状出现后存活时间超过1年。由于几乎所有这些病例都曾被误诊为MS，因此提出一种诊断方法，以帮助在明显蛛网膜下腔出血之前将脑干血管畸形与MS区分开来。
