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乳腺热成像与癌症风险预测

Breast thermography and cancer risk prediction.

作者信息

Gautherie M, Gros C M

出版信息

Cancer. 1980 Jan 1;45(1):51-6. doi: 10.1002/1097-0142(19800101)45:1<51::aid-cncr2820450110>3.0.co;2-l.

Abstract

Thermography makes a significant contribution to the evaluation of patients suspected of having breast cancer. The obviously abnormal thermogram carries with it a high risk of cancer. This report summarizes the results of patients with questionable or stage Th III thermograms. From approximately 58,000 patients, most of whom had breast complaints, examined between August 1965 and June 1977, the conditions or a group of 1,245 women were diagnosed at initial examination as either normal or benign disease by conventional means, including physical examination, mammography, ultrasonography, and fine needle aspiration or biopsy, when indicated, but nevertheless categorized as stage Th III indicating a questionable thermal anomaly. Within five years, more than a third of the group had histologically confirmed cancers. The more rapidly growing lesions with shorter doubling times usually show progressive thermographic abnormalities consistent with the increased metabolic heat production associated with such cancers. Thermography is useful not only as a predictor of risk factor for cancer but also to assess the more rapidly growing neoplasms.

摘要

热成像技术对疑似乳腺癌患者的评估具有重要作用。明显异常的热成像图提示患癌风险很高。本报告总结了热成像图可疑或为Ⅲ期的患者的检查结果。在1965年8月至1977年6月期间接受检查的约58000名患者中,大多数有乳腺相关症状,其中1245名女性在初诊时通过常规检查手段(包括体格检查、乳房X线摄影、超声检查以及必要时的细针穿刺或活检)被诊断为正常或良性疾病,但热成像图仍被归类为Ⅲ期,提示存在可疑的热异常。在五年内,该组超过三分之一的患者经组织学确诊为癌症。生长较快、倍增时间较短的病变通常会显示热成像图逐渐异常,这与这类癌症相关的代谢产热增加一致。热成像技术不仅可作为癌症风险因素的预测指标,还能用于评估生长较快的肿瘤。

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