Turner J D, Rogers W J, Mantle J A, Rackley C E, Russell R O
Chest. 1980 Jan;77(1):58-64. doi: 10.1378/chest.77.1.58.
We evaluated 198 consecutive survivors of acute myocardial infarction and performed selective coronary angiography in 117 of 131 (89 percent) patients who were deemed candidates for angiography by clinical criteria. Overall, left main CAD (greater than or equal to 70 percent stenosis) was found in ten patients (8.5 percent), three vessel CAD in 41 patients (35 percent), two vessel CAD in 37 patients (31.5 percent), single vessel disease in 27 patients (23 percent) and zero vessel disease in two patients (2 percent). Factors suggesting multivessel disease included older age, history of prior myocardial infarction, and post-infarction convalescence complicated by angina pectoris. Factors not discriminating between single and multivessel disease were sex, infarct extent (transmural vs non-transmural), (3) infarct location (anterior vs inferior), and post-infarction convalescence complicated by late arrhythmia or heart failure. This study demonstrates that multivessel coronary artery disease is common in survivors of myocardial infarction and is suggested by the occurrence of post-infarction angina and by the history of an antecedent myocardial infarction. Coronary angiography can be performed safely within 30 days after myocardial infarction in patients with an uncomplicated convalescence and with mild risk in those with a complicated convalescence.
我们评估了198例急性心肌梗死连续幸存者,并对131例(89%)经临床标准判定适合进行血管造影的患者中的117例进行了选择性冠状动脉造影。总体而言,10例患者(8.5%)发现左主干CAD(狭窄大于或等于70%),41例患者(35%)发现三支血管CAD,37例患者(31.5%)发现两支血管CAD,27例患者(23%)发现单支血管病变,2例患者(2%)未发现血管病变。提示多支血管病变的因素包括年龄较大、既往心肌梗死病史以及心肌梗死后恢复期并发心绞痛。不能区分单支和多支血管病变的因素有性别、梗死范围(透壁性与非透壁性)、梗死部位(前壁与下壁)以及心肌梗死后恢复期并发晚期心律失常或心力衰竭。本研究表明,多支冠状动脉疾病在心肌梗死幸存者中很常见,心肌梗死后心绞痛的发生以及既往心肌梗死病史提示存在多支冠状动脉疾病。对于恢复期无并发症的患者以及恢复期有并发症但风险较低的患者,可在心肌梗死后30天内安全地进行冠状动脉造影。