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内镜下乳头切开术治疗胆源性疾病所致急性胰腺炎(作者译)

[Endoscopic papillotomy for acute pancreatitis caused by biliary disease (author's transl)].

作者信息

Safrany L, Neuhaus B, Krause S, Portocarrero G, Schott B

出版信息

Dtsch Med Wochenschr. 1980 Jan 25;105(4):115-9. doi: 10.1055/s-2008-1070617.

Abstract

In 15 patients with acute pancreatitis caused by biliary disease endoscopic sphincterotomy was performed after diagnostic ERCP. All patients had a history of symptoms pointing to long-standing biliary disease, such as typical right-sided upper abdominal pain, signs of biliary stasis, and jaundice. An impacted solitary ampullar stone was demonstrated in eight patients while in seven several stones were found in the biliary tract. In one patient pancreaticogram also revealed a gall-stone which had slipped in Wirsung's duct. After endoscopic sphincterotomy and extraction of stone rapid and marked improvement occurred in all 15 patients and the biochemical abnormalities were restored towards normal. All patients became pain-free immediately after the procedure. The markedly raised levels of serum-alpha-amylase (mean of 21 700 U/l immediately before the procedure) fell tonormal values within 48 hours (400--3000 U/l). Endoscopic sphincterotomy is thus an alternative to early operation in acute pancreatitis of biliary origin.

摘要

在15例由胆道疾病引起的急性胰腺炎患者中,在诊断性内镜逆行胰胆管造影(ERCP)后进行了内镜括约肌切开术。所有患者均有提示长期胆道疾病的症状病史,如典型的右上腹疼痛、胆道淤滞体征和黄疸。8例患者显示有一枚嵌顿的壶腹结石,7例患者在胆道中发现数枚结石。1例患者的胰管造影还显示有一枚胆结石滑入了胰管。在内镜括约肌切开术和取石术后,所有15例患者均迅速且显著改善,生化异常恢复正常。所有患者术后立即不再疼痛。血清α淀粉酶水平显著升高(术前平均为21700 U/l)在48小时内降至正常范围(400 - 3000 U/l)。因此,内镜括约肌切开术是胆源性急性胰腺炎早期手术的一种替代方法。

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