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强音对内耳的影响:一项电生理学与超微结构相结合的研究

Effects of loud tones on the inner ear: a combined electrophysiological and ultrastructural study.

作者信息

Robertson D, Johnstone B M, McGill T J

出版信息

Hear Res. 1980 Jan;2(1):39-43. doi: 10.1016/0378-5955(80)90015-5.

DOI:10.1016/0378-5955(80)90015-5
PMID:7351390
Abstract

Guinea pigs were exposed to a 10 kHz pure tone and damage to the cochlea was investigated immediately after exposure, or after a recovery period ranging from 18-25 days. Structural damage was assessed using scanning electron microscopy and functional damage estimated using the N1 threshold audiogram. Exposure at 106 dB for 1 h caused obvious abnormalities of outer hair cell stereocilia. The location and extent of this damage was related to the immediate or long term deficits in the N1 threshold audiogram.

摘要

将豚鼠暴露于10千赫兹的纯音下,在暴露后立即或在18至25天的恢复期后,对耳蜗损伤情况进行研究。使用扫描电子显微镜评估结构损伤,使用N1阈值听力图估计功能损伤。在106分贝下暴露1小时会导致外毛细胞静纤毛出现明显异常。这种损伤的位置和程度与N1阈值听力图的即时或长期缺陷有关。

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