Schuckit M A, Miller P L, Berman J
J Clin Psychiatry. 1980 Jan;41(1):27-32.
This is a 3 year follow-up of the psychiatric status of 276 men age 65 and older who were originally seen as medical and surgical patients. Major psychiatric diagnoses were noted in 24% of the individuals, these being fairly evenly divided between active alcoholism, affective disorder, atherosclerotic dementia, or a past history of alcoholism, and a heterogeneous category, composed mostly of individuals with senile dementia. Over the 3 years, approximately one-quarter of the sample who had originally been free of psychopathology became ill, most with an affective disorder or an organic brain syndrome. A high level of diagnostic consistency was noted over 3 years for the individuals originally noted to be psychiatrically ill. The follow-up demonstrated an unexpectedly bleak prognosis for the individuals with affective disorder. The reasons for this finding are explored.
这是对276名65岁及以上男性精神病状况的3年随访,这些男性最初是作为内科和外科患者就诊的。24%的个体被诊断出患有主要精神疾病,这些疾病在酒精依赖、情感障碍、动脉粥样硬化性痴呆、有酗酒史以及一个异质性类别(主要由患有老年痴呆症的个体组成)之间分布较为均匀。在这3年中,最初没有精神病理学症状的样本中约有四分之一患病,大多数患的是情感障碍或器质性脑综合征。对于最初被诊断为患有精神疾病的个体,3年期间的诊断一致性较高。随访结果显示,情感障碍患者的预后出乎意料地严峻。本文探讨了这一发现的原因。