Shea S M
Yale J Biol Med. 1978 May-Jun;51(3):321-3.
Changes of glomerular volume in rats were measured up to 21 weeks following subtotal nephrectomy, using morphometric methods. A linear increase of glomerular volume was observed between 2 and 21 weeks after subtotal nephrectomy. This progressive increase in glomerular volume may reflect compensatory hemodynamic changes leading to an increased single nephron glomerular filtration rate.
采用形态计量学方法,对大鼠肾次全切除术后长达21周的肾小球体积变化进行了测量。在肾次全切除术后2至21周期间,观察到肾小球体积呈线性增加。肾小球体积的这种渐进性增加可能反映了代偿性血流动力学变化,导致单个肾单位肾小球滤过率增加。