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肾单位慢性减少:电子显微镜下的肾小球形态测定

Chronic reduction of renal mass: glomerular morphometry by electron microscopy.

作者信息

Shea S M

出版信息

Yale J Biol Med. 1978 May-Jun;51(3):321-3.

Abstract

Changes of glomerular volume in rats were measured up to 21 weeks following subtotal nephrectomy, using morphometric methods. A linear increase of glomerular volume was observed between 2 and 21 weeks after subtotal nephrectomy. This progressive increase in glomerular volume may reflect compensatory hemodynamic changes leading to an increased single nephron glomerular filtration rate.

摘要

采用形态计量学方法,对大鼠肾次全切除术后长达21周的肾小球体积变化进行了测量。在肾次全切除术后2至21周期间,观察到肾小球体积呈线性增加。肾小球体积的这种渐进性增加可能反映了代偿性血流动力学变化,导致单个肾单位肾小球滤过率增加。

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RENAL AND ADRENAL RELATIONSHIPS IN COMPENSATORY HYPERPLASIA.代偿性增生中肾脏与肾上腺的关系
Proc Soc Exp Biol Med. 1965 Feb;118:342-6. doi: 10.3181/00379727-118-29837.
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Dynamics of glomerular ultrafiltration in the rat. VII. Response to reduced renal mass.
Am J Physiol. 1974 Sep;227(3):556-62. doi: 10.1152/ajplegacy.1974.227.3.556.

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