代偿性肾肥大中的信使核糖核酸
Messenger RNA in compensatory renal hypertrophy.
作者信息
Ouellette A J
出版信息
Yale J Biol Med. 1978 May-Jun;51(3):413-8.
Abstract
Experiments that deal with the stability of messenger RNA (mRNA) in normal mouse kidney, and, to some extent, the stability of mRNA during renal growth will be described. We have found a population of mRNA in the cytoplasm of mouse kidney that is short-lived. Such a class of rapidly metabolized mRNA could play an adaptive role at the translational or cytoplasmic level in determining gene expression and may be important during the early phases of compensatory hypertrophy.
摘要
将描述有关正常小鼠肾脏中信使核糖核酸（mRNA）稳定性的实验，以及在一定程度上肾脏生长过程中mRNA的稳定性。我们发现在小鼠肾脏细胞质中有一群寿命较短的mRNA。这类快速代谢的mRNA可能在翻译或细胞质水平上对决定基因表达起到适应性作用，并且在代偿性肥大的早期阶段可能很重要。
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