Tsuji M, Hayashi T, Yamamoto S, Sakata Y, Toshida T
Int Arch Allergy Appl Immunol. 1977;55(1-6):78-81. doi: 10.1159/000231912.
IgE antibodies to Ascaris antigens were detected by radioallergosorbent test (RAST) in the serum obtained from a person experimentally sensitized with Ascaris suum antigens prepared from the body fluid of worms. This serum passively sensitized human skin in vitro and histamine release from the sensitized skin was observed by challenge with antigens. The allergenicity of A. suum antigens was present over a very broad spectrum of molecular size. The present results suggest that specific IgE antibodies to Ascaris antigens might be in Ascaris-infected patients and allergic symptoms which belong to type 1 reaction might be mediated by IgE in these patients.
通过放射变应原吸附试验（RAST），在一名用从猪蛔虫体液制备的猪蛔虫抗原进行实验性致敏的人的血清中，检测到了针对猪蛔虫抗原的IgE抗体。这种血清在体外被动致敏人体皮肤，通过用抗原激发观察到致敏皮肤释放组胺。猪蛔虫抗原的致敏性存在于非常广泛的分子大小范围内。目前的结果表明，蛔虫感染患者体内可能存在针对蛔虫抗原的特异性IgE抗体，并且这些患者中属于1型反应的过敏症状可能由IgE介导。
