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子宫切除术后发生脓肿的女性对脆弱拟杆菌的血清抗体反应。

Serum antibody response to Bacteroides fragilis in women with abscesses following hysterectomy.

作者信息

Polk B F, Kasper D L, Shapiro M, Tager I B, Schoenbaum S C, Goldstein P R

出版信息

Obstet Gynecol. 1980 Feb;55(2):163-6.

PMID:7352073
Abstract

To determine the role of Bacteroides fragilis in the development of infectious complications following hysterectomy, serum antibody to the capsular polysaccharide was measured with a radioactive antigen-binding assay in 53 women before and several days after surgery. Patients with postoperative abscess formation had a significantly greater mean increase in antibody concentration (4.91 micrograms/ml) than those without complications (0.62 micrograms/ml), those with wound infection (1.90 micrograms/ml), those with pelvic cellulitis (0.63 micrograms/ml), and those with febrile morbidity (0.95 micrograms/ml). There were no significant differences among the latter 4 groups. The authors conclude that B fragilis may play an important role in abscess formation following hysterectomy, but is infrequently involved in other infectious complications of this procedure.

摘要

为确定脆弱拟杆菌在子宫切除术后感染性并发症发生过程中的作用,采用放射性抗原结合试验对53名女性在手术前及术后数天检测其抗荚膜多糖的血清抗体。术后形成脓肿的患者抗体浓度平均升高幅度(4.91微克/毫升)显著大于无并发症患者(0.62微克/毫升)、伤口感染患者(1.90微克/毫升)、盆腔蜂窝织炎患者(0.63微克/毫升)及发热性疾病患者(0.95微克/毫升)。后4组之间无显著差异。作者得出结论,脆弱拟杆菌可能在子宫切除术后脓肿形成中起重要作用,但很少参与该手术的其他感染性并发症。

相似文献

1
Serum antibody response to Bacteroides fragilis in women with abscesses following hysterectomy.子宫切除术后发生脓肿的女性对脆弱拟杆菌的血清抗体反应。
Obstet Gynecol. 1980 Feb;55(2):163-6.
2
Cellular control of abscess formation: role of T cells in the regulation of abscesses formed in response to Bacteroides fragilis.脓肿形成的细胞调控:T细胞在脆弱拟杆菌诱导形成的脓肿调节中的作用
J Immunol. 1986 Jul 1;137(1):341-6.
3
The humoral antibody response to Bacteroides fragilis infections in humans.人类对脆弱拟杆菌感染的体液抗体反应。
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Encapsulation and protection against phagocytosis by Bacteroides fragilis.脆弱拟杆菌的包囊化及抗吞噬作用
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Infection with Bacteroides fragilis: pathogenesis and immunoprophylaxis in an animal model.脆弱拟杆菌感染:动物模型中的发病机制与免疫预防
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T cell regulation of Bacteroides fragilis-induced intraabdominal abscesses.T细胞对脆弱拟杆菌诱导的腹腔内脓肿的调节作用。
Rev Infect Dis. 1990 Jan-Feb;12 Suppl 2:S178-84.
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Evidence for T cell-dependent immunity to Bacteroides fragilis in an intraabdominal abscess model.腹腔脓肿模型中针对脆弱拟杆菌的T细胞依赖性免疫的证据。
J Clin Invest. 1982 Jan;69(1):9-16. doi: 10.1172/jci110445.
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Quantitative determination of the serum antibody response to the capsular polysaccharide of Bacteroides fragilis subspecies fragilis in women with pelvic inflammatory disease.盆腔炎女性血清中针对脆弱拟杆菌脆弱亚种荚膜多糖抗体反应的定量测定。
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Preexposure of the peritoneum to live bacteria increases later mixed intraabdominal abscess formation and delays mortality.腹膜预先暴露于活细菌会增加之后混合性腹腔内脓肿的形成并延迟死亡。
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