Wight P A, Siller W G
Vet Pathol. 1980 Jan;17(1):29-39. doi: 10.1177/030098588001700103.
Deep pectoral myopathy occurred in 39 of 204 apparently healthy and 46 of 146 ill, adult broiler breeders from Poultry Research Centre flocks. Both sexes and two commercial strains were similarly affected. The myopathy was not associated with any disease except pododermatitis. The supracoracoid was the only muscle affected. It was bilaterally involved in 33 chickens. The lesions were grouped macroscopically into three categories: acute oedema progressing to a green necrosis, centrally located cicatrix, and replacement of the caudal region by fibroadipose tissue. Microscopcially the green lesion consisted of necrotic, anucleate muscle fibres devoid of inflammatory cells and surrounded by a fibrous capsule that had a reactive inner border and externally abutted on normal and regenerating muscle or fibro-adipose tissue. Considered with the ultrastructural findings of early loss of glycogen and disintegration of sarcoplasmic reticulum, mitochondria, nuclei and Z lines, these findings indicate that the condition is an ischaemic necrosis. There was no evidence that its primary cause was occlusive vascular lesions. The muscle was able to regenerate unless extensive secondary neurological lesions were present.
来自家禽研究中心鸡群的204只外观健康的成年肉种鸡中有39只出现深部胸肌病，146只患病成年肉种鸡中有46只出现该病。两性以及两个商业品系受影响情况相似。除了足皮炎外，这种肌病与任何疾病均无关联。胸上肌是唯一受影响的肌肉。33只鸡双侧受累。病变在宏观上分为三类：急性水肿发展为绿色坏死、中央部位的瘢痕以及尾侧区域被纤维脂肪组织替代。在显微镜下，绿色病变由坏死的、无核的肌纤维组成，没有炎症细胞，周围有一层纤维性包膜，其内侧边缘有反应性，外侧邻接正常和再生的肌肉或纤维脂肪组织。结合糖原早期丢失以及肌浆网、线粒体、细胞核和Z线解体的超微结构发现，这些结果表明该病是一种缺血性坏死。没有证据表明其主要病因是闭塞性血管病变。除非存在广泛的继发性神经病变，否则肌肉能够再生。
