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豚鼠的亚临床坏血病

Subclinical scurvy in the guinea pig.

作者信息

Clarke G L, Allen A M, Small J D, Lock A

出版信息

Vet Pathol. 1980 Jan;17(1):40-4. doi: 10.1177/030098588001700104.

DOI:10.1177/030098588001700104
PMID:7352362
Abstract

Twenty-eight guinea pigs from nine episodes of subclinical scurvy had diarrhea, weight loss and dehydration. The classical signs of scurvy were not seen. Microscopically the epiphyses were attenutated and irregular. The amount of osteoid was less than normal. Many guinea pigs had acute enteritis. In some there were many hemosiderin-laden macrophages in the intestinal lamina propria. All episodes were associated with either autoclaving food without adequate supplementation or other inadequate feed management practices.

摘要

来自9例亚临床坏血病发作的28只豚鼠出现腹泻、体重减轻和脱水。未观察到坏血病的典型症状。显微镜下可见骨骺变细且不规则。类骨质的量低于正常水平。许多豚鼠患有急性肠炎。部分豚鼠的肠固有层中有许多含铁血黄素巨噬细胞。所有发作均与未充分补充营养而对食物进行高压灭菌或其他不当的饲料管理做法有关。

相似文献

1
Subclinical scurvy in the guinea pig.豚鼠的亚临床坏血病
Vet Pathol. 1980 Jan;17(1):40-4. doi: 10.1177/030098588001700104.
2
A comparison of circulatory and calcification changes induced by the mandibular condyle, tibial epiphyseal and articular cartilages of the guinea pig by the onset and healing of scurvy.豚鼠下颌髁突、胫骨骨骺和关节软骨在坏血病发生和愈合过程中所引起的循环和钙化变化的比较。
Arch Oral Biol. 1969 Dec;14(12):1373-82. doi: 10.1016/0003-9969(69)90253-2.
3
Dietary cholesterol, sex and scurvy in guinea-pigs.豚鼠的膳食胆固醇、性别与坏血病
Nature. 1973 Apr 20;242(5399):521-2. doi: 10.1038/242521a0.
4
Histological and histochemical investigations of the guinea-pig adrenal cortex in experimental scurvy.
Folia Histochem Cytochem (Krakow). 1970;8(3):287-316.
5
Diseases of guinea-pigs.豚鼠疾病。
Vet Rec. 1976 May 22;98(21):418-23. doi: 10.1136/vr.98.21.418.
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Fine structure of epiphyseal cartilage in experimental scurvy.实验性坏血病中骺软骨的精细结构
J Pathol. 1970 Dec;102(4):219-27. doi: 10.1002/path.1711020406.
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The phosphates and other compounds in the gastrocnemius muscle of scorbutic guinea pig.坏血病豚鼠腓肠肌中的磷酸盐及其他化合物。
Fed Proc. 1946;5(1 Pt 2):49.
8
Mortality rate in male and female guinea-pigs on a scorbutogenic diet.食用致坏血病饮食的雄性和雌性豚鼠的死亡率。
Nature. 1973 Apr 20;242(5399):522-3. doi: 10.1038/242522a0.
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Ocular Surface Disease in Rodents (Guinea Pigs, Mice, Rats, Chinchillas).啮齿动物(豚鼠、小鼠、大鼠、龙猫)的眼表疾病
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Vitamin C Depletion in Prenatal Guinea Pigs as a Model of Lissencephaly Type II.产前豚鼠维生素C缺乏作为II型无脑回畸形模型
Vet Pathol. 2015 Nov;52(6):1263-71. doi: 10.1177/0300985814561270. Epub 2014 Dec 8.

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