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啮齿动物（豚鼠、小鼠、大鼠、龙猫）的眼表疾病

Ocular Surface Disease in Rodents (Guinea Pigs, Mice, Rats, Chinchillas).

作者信息

Monk Caroline

机构信息

Ophthalmology, BluePearl Veterinary Partners, 1071 Howell Mill Road Northwest, Atlanta, GA 30318, USA.

出版信息

Vet Clin North Am Exot Anim Pract. 2019 Jan;22(1):15-26. doi: 10.1016/j.cvex.2018.08.001.

DOI:10.1016/j.cvex.2018.08.001
PMID:30454759
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7110570/
Abstract

This article discusses the clinical appearance, differential diagnoses, and treatment considerations of corneal disease in the most common domesticated species of rodent: mouse, rat, chinchilla, and guinea pig. Many corneal diseases are related to inbred strains of either research or pet rodents. Diseases are complicated by husbandry and treatment-related challenges in this small, social species. This article is broken down by species, first discussing normal anatomy, then discussing commonly encountered diseases, and concluding with treatment considerations.

摘要

本文讨论了最常见的家养啮齿动物物种（小鼠、大鼠、龙猫和豚鼠）角膜疾病的临床表现、鉴别诊断和治疗注意事项。许多角膜疾病与研究用或宠物用啮齿动物的近交品系有关。在这个小型群居物种中，饲养和治疗相关的挑战使疾病变得复杂。本文按物种分类进行阐述，首先讨论正常解剖结构，然后讨论常见疾病，最后得出治疗注意事项。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac96/7110570/88ac294d2f50/gr5_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac96/7110570/a32c7c151c14/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac96/7110570/349cc87db19c/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac96/7110570/dacd583bc2ad/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac96/7110570/de3804ec6fa3/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac96/7110570/88ac294d2f50/gr5_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac96/7110570/a32c7c151c14/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac96/7110570/349cc87db19c/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac96/7110570/dacd583bc2ad/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac96/7110570/de3804ec6fa3/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac96/7110570/88ac294d2f50/gr5_lrg.jpg

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The Balance of Th1/Th2 and LAP+Tregs/Th17 Cells Is Crucial for Graft Survival in Allogeneic Corneal Transplantation.Th1/Th2与LAP+调节性T细胞/Th17细胞的平衡对于同种异体角膜移植中移植物的存活至关重要。
J Ophthalmol. 2018 Feb 8;2018:5404989. doi: 10.1155/2018/5404989. eCollection 2018.
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Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma.调控小鼠角膜厚度的基因组位点将 POU6F2 鉴定为潜在的青光眼发病风险因素。
PLoS Genet. 2018 Jan 25;14(1):e1007145. doi: 10.1371/journal.pgen.1007145. eCollection 2018 Jan.
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Epidemiology of bacterial conjunctivitis in chinchillas (Chinchilla lanigera): 49 cases (2005 to 2015).
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J Ophthalmol. 2022 May 26;2022:6955461. doi: 10.1155/2022/6955461. eCollection 2022.
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Dexmedetomidine and Tear Production: Evaluation in Dogs as Spontaneous Model for Ocular Surface Disorders.右美托咪定与泪液分泌：以犬作为眼表疾病自发模型的评估
Vet Sci. 2021 Feb 16;8(2):28. doi: 10.3390/vetsci8020028.
龙猫（Chinchilla lanigera）细菌性结膜炎的流行病学：49例（2005年至2015年）
J Small Anim Pract. 2017 Apr;58(4):238-245. doi: 10.1111/jsap.12644.
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Invest Ophthalmol Vis Sci. 2015 Jan 13;56(2):1097-107. doi: 10.1167/iovs.14-15596.
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