Chilton R J, Oliveros R A, Stutts B S, Beckmann C H, Boucher C A
Arch Intern Med. 1980 Feb;140(2):240-3. doi: 10.1001/archinte.140.2.240.
The ratio of the preejection period to the left ventricular ejection time (PEP/LVET), obtained from the aortic root echocardiogram, was studied immediately before and after left ventricular (LV) cineangiography in 23 patients with documented coronary artery disease. The initial PEP/LVET ratio was inversely related to LV ejection fraction (r = -.78, P less than or equal to .001). Repeat measurements taken 60 s after angiography showed a significant decrease from a mean value of .36 +/- .13 to .27 +/- .08 (P less than or equal to .005). Furthermore, when patients were divided into those with an initial PEP/LVET value above and below 0.40, those with a higher value showed a significantly greater decrease following contrast left ventriculography (mean decrease, 0.16 vs 0.06, P less than or equal to .01). This study indicates that systolic time intervals derived from echocardiography are a reliable noninvasive measure of LV function, and that ventricular function improves following left ventriculography, with the degree of improvement being inversely related to initial function.
在23例确诊为冠状动脉疾病的患者中，于左心室（LV）心血管造影前后，即刻研究了从主动脉根部超声心动图获得的射血前期与左心室射血时间之比（PEP/LVET）。初始PEP/LVET比值与左心室射血分数呈负相关（r = -0.78，P≤0.001）。血管造影后60秒进行的重复测量显示，该比值从平均值0.36±0.13显著降至0.27±0.08（P≤0.005）。此外，当将患者分为初始PEP/LVET值高于和低于0.40两组时，初始值较高的患者在行对比剂左心室造影后下降幅度明显更大（平均下降值分别为0.16和0.06，P≤0.01）。本研究表明，超声心动图得出的收缩期时间间期是左心室功能可靠的无创测量指标，并且左心室造影后心室功能改善，改善程度与初始功能呈负相关。
