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大鼠小肠的糖脂。一种新型血型H活性三糖基神经酰胺的特性

Glycolipids of rat small intestine. Characterization of a novel blood group H-active triglycosylceramide.

作者信息

Breimer M E, Hansson G C, Karlsson K A, Leffler H

出版信息

Biochim Biophys Acta. 1980 Jan 18;617(1):85-96. doi: 10.1016/0005-2760(80)90226-x.

Abstract

A novel blood group H-active triglycosylceramide has been isolated from rat small intestine. It was present exclusively in the epithelial cells. The structure was established by mass spectrometry, NMR spectroscopy and degradative methods to the Fucp alpha 1 leads to 2Galp beta 1 leads to 4Glcp beta 1 leads to 1Cer. The lipophilic part was made up of mainly trihydroxy base (phytosphingosine) and 16 : 0--24 : 0 fatty acids.

摘要

一种新型的具有血型H活性的三糖基神经酰胺已从大鼠小肠中分离出来。它仅存在于上皮细胞中。通过质谱、核磁共振光谱和降解方法确定其结构为Fucpα1→2Galpβ1→4Glcpβ1→1Cer。亲脂部分主要由三羟基碱(植物鞘氨醇)和16:0-24:0脂肪酸组成。

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